Publications

During the runtime of the EQIPD project, members have published a total of 34 articles connected with the project.

2024

Reiber, M.,  Stirling, H.,  Ahuis, T. P.,  Arias, W.,  Aulehner, K.,  Dreßler, U.,  Kas, M. J. H.,  Kela, J.,  Kerker, K.,  Kuosmanen, T.,  Lorenz, H.,  Pennington, A. T.,  von Rüden, E.-L.,  Schauerte, H.,  Seiffert, I.,  Talbot, S. R.,  Torturo, C.,  Virtanen, S., Waldron, A.-M., …  Potschka, H. (2024).  A systematic assessment of robustness in CNS safety pharmacology. British Journal of Pharmacology,  1–16. https://doi.org/10.1111/bph.17358

2022

María Arroyo-Araujo, Martien J.H. Kas, The perks of a quality system in academia,
Neuroscience Applied, Volume 1, 2022,100001,ISSN 2772-4085, https://doi.org/10.1016/j.nsa.2022.100001.

Arroyo-Araujo M, Voelkl B, Laloux C, Novak J, Koopmans B, Waldron A-M, et al. (2022) Systematic assessment of the replicability and generalizability of preclinical findings: Impact of protocol harmonization across laboratory sites. PLoS Biol 20(11): e3001886. https://doi.org/10.1371/journal.pbio.3001886

Vollert, J., Macleod, M., Dirnagl, U. et al. The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments. Nat Methods 19, 1334–1337 (2022). https://doi.org/10.1038/s41592-022-01615-y

2021

Restivo L, Gerlach B, Tsoory M, et al. (2021). Towards best practices in research: Role of academic core facilities. EMBO Rep. 12:e53824. DOI: 10.15252/embr.202153824 

Bespalov A, Bernard R, Gilis A et al. (2021). Introduction to the EQIPD quality system. eLife. 10:e63294. DOI: 10.7554/eLife.63294

Sil A, Erfani A, Lamb N et al. (2021). Sex differences in behaviour and molecular pathology in the 5XFAD model. bioRxiv. 04.29.440396. DOI: 10.1101/2021.04.29.440396

2020

Erdogan BR, Vollert J & Michel MC (2020). Choice of y-axis can mislead readers. Naunyn-Schmiedeberg’s Arch Pharmacol. 393, 1769–1772. DOI: 10.1007/s00210-020-01926-x

Voelkl B, Altman NS, Forsman A et al. (2020). Reproducibility of animal research in light of biological variation. Nat Rev Neurosci. 21, 384–393. DOI: 10.1038/s41583-020-0313-3

Vollert J, Schenker E, Macleod M The EQIPD WP3 study group members, et al. (2020). Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals. BMJ Open Science. 4: e100046. DOI: 10.1136/bmjos-2019-100046

Amiri M, Murgas S, Stang A, Michel MC (2020). Do overactive bladder symptoms and their treatment‐associated changes exhibit a normal distribution? Implications for analysis and reporting. Neurourology and Urodynamics. 39: 754– 761. DOI: 10.1002/nau.24275

Bespalov A, Michel MC, Steckler T (eds). Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol 257. Springer Open 2020, Cham, Switzerland. ISBN: 978-3-030-33658-5

Erdogan BR, Karaomerlioglu I, Yesilyurt ZE et al. (2020). Normalization of organ bath contraction data for tissue specimen size: does one approach fit all? Naunyn-Schmiedeberg’s Arch Pharmacol 393: 243–251. DOI: 10.1007/s00210-019-01727-x

Michel MC, Murphy TJ and Motulsky HJ (2020). New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.Molecular Pharmacology. 97 (1): 49-60. DOI: 10.1124/mol.119.118927

Michel MC, Murphy TJ and Motulsky HJ (2020). New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.Drug Metabolism and Disposition. 48 (1) 64-74. DOI: 10.1124/dmd.119.090027

2019

Bespalov A, Steckler T, Skolnick P (2019). Be positive about negatives-recommendations for the publication of negative (or null) results. Eur Neuropsychopharmacol. 29 (12): 1312-1320. DOI: 10.1016/j.euroneuro.2019.10.007

Bespalov A, Wicke K, Castagné V (2019). Blinding and Randomization. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_279

Bongiovanni S, Purdue R, Kornienko O, and Bernard R (2019). Quality in Non-GxP Research Environment. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_274

Dirnagl U (2019). Resolving the Tension Between Exploration and Confirmation in Preclinical Biomedical Research. In: Bespalov A., Michel M., Steckler T. (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer, Cham, Switzerland. DOI: 10.1007/164_2019_278

Erdogan BR, Michel MC (2019). Building Robustness into Translational Research. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open. Cham, Switzerland. DOI: 10.1007/164_2019_283

Gerlach B, Untucht C, Stefan A (2019). Electronic Lab Notebooks and Experimental Design Assistants. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_287

Gilis A (2019). Quality Governance in Biomedical Research. In: Bespalov A., Michel M., Steckler T. (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open.Cham, Switzerland. DOI: 10.1007/164_2019_291

Guillén J and Steckler T (2019). Good Research Practice: Lessons from Animal Care and Use. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_292

Hair K, Almenar JP and Sena E on behalf of the EQIPD WP2 study group (2019). Synaptic dysfunction and memory impairments in transgenic Alzheimer’s disease models: A systematic review protocol. OSF Stroage. DOI: 10.17605/OSF.IO/PKWH8

Huang W, Percie du Sert N, Vollert J, and Rice ASC (2019). General Principles of Preclinical Study Design. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_277

Kabitzke P, Cheng KM, and Altevogt B (2019). Guidelines and Initiatives for Good Research Practice. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_275

Lefevre IA and Balice-Gordon RJ (2019). Learning from Principles of Evidence-Based Medicine to Optimize Nonclinical Research Practices. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_276

Macleod M, Steckler T (2019). A European initiative to unclog pipeline for new medicines. Nature. 568 (7753): 458. DOI: 10.1038/d41586-019-01293-5

Macleod MR, Tanriver-Ayder E, Hair K, and Sena E (2019). Design of Meta-Analysis Studies. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol.  257. Springer Open, Cham, Switzerland. DOI: 10.1007/164_2019_289

Sena E and Hair K on behalf of the WP2 study group (2019). The open field test protocol in transgenic Alzheimer’s disease models: A systematic review protocol. OSF Storage. DOI: 10.17605/OSF.IO/E4WBF

Voehringer P and Nicholson JR (2019). Minimum Information in In Vivo Research. In: Bespalov A, Michel MC, Steckler T (eds) Good Research Practice in Non-Clinical Pharmacology and Biomedicine. Handbook of Experimental Pharmacology, Vol. 257. Springer Open. Cham, Switzerland. DOI: 10.1007/164_2019_285

2018

Vollert J, Schenker E, Macleod M, Bespalov A, Wuerbel H, Michel MC, Dirnagl U, Potschka H, Wever KE, Steckler T, Altevogt B, Rice A (2018). Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals. BMJ Open Science. 2 (1). e000004. DOI: 10.1136/bmjos-2018-000004

Steckler T, Macleod M, Kas MJ, Gilis A, Wever KE (2018). European Quality in Preclinical Data (EQIPD): een breed consortium voor het verbeteren van de kwaliteit van proefdieronderzoek. Biotechniek. 57 (2): 18-23.

Motulsky HJ, Michel MC (2018). Commentary on the BJP’s new statistical reporting guidelines. British Journal of Pharmacology. 175 (18): 3636-3637. DOI: 10.1111/bph.14441